NEET Biology: Cell - The Unit of Life - NCERT Notes & 100 MCQ Quiz

NEET Biology: Cell - The Unit of Life

CELL: THE UNIT OF LIFE

NCERT Masterclass & NEET Biology Study Module

1. Cell Theory

Formulated by Matthias Schleiden (Botanist, 1838) and Theodore Schwann (Zoologist, 1839). Schwann reported that cells have a thin outer layer (plasma membrane) and that plant cells uniquely possess a cell wall.

Rudolf Virchow (1855) modified it:
"Omnis cellula-e cellula"
(All cells arise from pre-existing cells).

2. Prokaryotic Cells

Includes bacteria, blue-green algae, mycoplasma, and PPLO. They lack a membrane-bound nucleus and organelles. Genetic material is naked (Nucleoid).

  • Cell Envelope: Consists of tightly bound 3-layered structure: Outer Glycocalyx (Slime layer or tough Capsule), middle Cell wall, and inner Plasma membrane.
  • Mesosomes: Infoldings of the plasma membrane (vesicles, tubules, lamellae). Help in cell wall formation, DNA replication, respiration, and secretion.
  • Plasmids: Small, circular, extrachromosomal DNA that confers unique phenotypic characters (like antibiotic resistance).
  • Surface Structures: Flagella (for motility; composed of filament, hook, basal body). Pili (tubular, for mating) and Fimbriae (bristle-like, for attachment to rocks/host tissues).
  • Ribosomes: 70S type (50S + 30S subunits). Site of protein synthesis.

3. Eukaryotic Cells: Cell Membrane & Cell Wall

Eukaryotes include Protists, Fungi, Plants, and Animals. They possess organized nuclei with a nuclear envelope and complex compartmentalization.

Fluid Mosaic Model (Singer and Nicolson, 1972):
"Protein icebergs floating in a sea of lipids." The quasi-fluid nature of lipids enables lateral movement of proteins.
  • Lipids: Arranged in a bilayer. Polar (hydrophilic) heads outwards, non-polar (hydrophobic) tails inwards (protects from aqueous environment).
  • Proteins: Integral (partially or totally buried) and Peripheral (lie on the surface).
Fluid Mosaic Model of Plasma Membrane Integral Protein Peripheral Polar Head (Hydrophilic) Tails (Hydrophobic) • Selectively permeable • Active transport (ATP used) • Osmosis (Water movement)

Cell Wall: Non-living rigid structure.
- Algae: Cellulose, galactans, mannans, and minerals like $CaCO_3$.
- Plants: Cellulose, hemicellulose, pectins, and proteins.
- Middle Lamella: Made of calcium pectate, glues neighboring cells together. Plasmodesmata connect the cytoplasm of adjacent cells.

4. The Endomembrane System

Organelles whose functions are coordinated: ER, Golgi complex, Lysosomes, and Vacuoles.

  • Endoplasmic Reticulum (ER): Network of tiny tubular structures. Rough ER (RER) has ribosomes (protein synthesis). Smooth ER (SER) lacks ribosomes (lipid and steroid hormone synthesis).
  • Golgi Apparatus: Discovered by Camillo Golgi. Consists of flat, disc-shaped sacs (cisternae). Important site of formation of glycoproteins and glycolipids. Modifies and packages materials. Has a forming (cis) face and maturing (trans) face.
  • Lysosomes: Membrane-bound vesicular structures containing hydrolytic enzymes (lipases, proteases, carbohydrases) optimally active at acidic pH.
  • Vacuoles: Bound by a single membrane called tonoplast. In plant cells, it can occupy 90% of the volume. Tonoplast facilitates transport of ions against concentration gradients. In Amoeba, the contractile vacuole helps in excretion.

5. Mitochondria and Plastids

Both are double membrane-bound and semi-autonomous (contain their own circular DNA and 70S ribosomes).

  • Mitochondria: Powerhouses of the cell. Inner membrane forms infoldings called cristae to increase surface area. Produce ATP.
  • Plastids: Found in plant cells and euglenoids.
    • Chloroplasts: Contain chlorophyll. Inner space is stroma. Thylakoids are arranged in stacks called grana.
    • Chromoplasts: Contain fat-soluble carotenoid pigments (carotene, xanthophylls) giving yellow/orange/red colors.
    • Leucoplasts: Colorless plastids for storage. Amyloplasts (carbohydrates/starch), Elaioplasts (oils/fats), Aleuroplasts (proteins).

6. Nucleus & Chromosomes

Nucleus was discovered by Robert Brown. Material inside named Chromatin by Flemming. Has a double-layered nuclear envelope with nuclear pores.

Nucleolus: Non-membranous, spherical body inside the nucleus. It is the site for active ribosomal RNA (rRNA) synthesis.

Types of Chromosomes (Based on Centromere) Metacentric (Middle - Equal arms) Sub-metacentric (Slightly away from middle) Acrocentric (Close to its end) Telocentric (Terminal centromere) Centromere
Important Distinctions:
  • Cilia and Flagella: Core is called axoneme. Has 9+2 array of microtubules. Base is called basal body.
  • Centrosome and Centrioles: Non-membranous. Made of 9 evenly spaced peripheral fibrils (triplets). Array is 9+0. Arranged like a cartwheel. Form the spindle apparatus during cell division in animal cells.
  • Satellite: Some chromosomes have a non-staining secondary constriction at a constant location, giving the appearance of a small fragment called the satellite.
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🚀 NEET CELL UNIT OF LIFE MEGA QUIZ (100 MCQ)

Solve the 5 parts below to master Cell Theory, Organelles, and Chromosomes.

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